Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fibrotic response as a distinguishing feature of resistance and susceptibility to pulmonary infection with Mycobacterium tuberculosis in mice.

Infection and immunity - 1 Jan 2008

Marquis Jean-François, Nantel André, LaCourse Ronald, Ryan Lynn, North Robert J, Gros Philippe

Abstract excerpt

The differential susceptibility of inbred mouse strains DBA/2J (susceptible) and C57BL/6J (resistant) to pulmonary tuberculosis following aerosol infection is under complex genetic control. In this report, transcriptional profiling with RNAs from Mycobacterium tuberculosis-infected lungs was used to investigate the physiological response, cell type, and biochemical pathways underlying differential susceptibility...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fibrosis
Share to Gene Expression Profiling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Mice, Inbred DBA

Share to Mycobacterium tuberculosis

Share to Oligonucleotide Array Sequence Analysis

Share to Tuberculosis, Pulmonary

Source

Open in PubMed Open full text

Identifiers

PMID: 17938213
DOI: 10.1128/IAI.00369-07
PMCID: PMC2223652

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fibrotic response as a distinguishing feature of resistance and susceptibility to pulmonary infection with Mycobacterium tuberculosis in mice.PMID 17938213Read ↗

Immune Response to <i>Mycobacterium tuberculosis</i> and Identification of Molecular Markers of DiseaseSemantic proximity Read ↗

Resistance and susceptibility to tuberculosis analysed at the transcriptome level: lessons from mouse macrophages.Semantic proximity Read ↗

Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosisSemantic proximity Read ↗

Spatial transcriptomic analysis of HIV and tuberculosis coinfection in a humanized mouse model reveals unique transcription patterns, immune responses and early morphological alterationsSemantic proximity Read ↗

Genetically determined susceptibility to tuberculosis in mice causally involves accelerated and enhanced recruitment of granulocytes.Semantic proximity Read ↗

Genetic control of susceptibility to infection with Mycobacterium tuberculosis in mice.Semantic proximity Read ↗

Analysis of the lung transcriptome in Mycobacterium tuberculosis-infected mice reveals major differences in immune response pathways between TB-susceptible and resistant hosts.Semantic proximity Read ↗

Tuberculosis susceptibility in genetically diverse mice reveals functional diversity of neutrophilsSemantic proximity Read ↗

Aberrant adaptive immune response underlies genetic susceptibility to tuberculosis.Semantic proximity Read ↗

Mouse models for the genetic study of tuberculosis susceptibility.Semantic proximity Read ↗

Susceptibility to tuberculosis: a locus on mouse chromosome 19 (Trl-4) regulates Mycobacterium tuberculosis replication in the lungs.Semantic proximity Read ↗

Interleukin-1 receptor antagonist is a conserved early factor for exacerbating tuberculosis susceptibilitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.