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Article

Animal Models of Lupus and Lupus Nephritis

30 Apr 2015

Abstract excerpt

This article reviews the commonly used murine strains for studying lupus and lupus nephritis, including strains that develop lupus spontaneously, congenic strains, induced models of lupus, as well as genetically engineered mouse models of lupus bearing transgenes or knockouts. The review then summarizes the main cellular and molecular pathways that lead to the pathogenesis of this autoimmune disease, including...

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Identifiers

PMID: 25777751
DOI: 10.2174/1381612821666150316115727

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