Article
The genotype determines the B cell response in mercury-treated mice.
International archives of allergy and immunology - 1 Aug 1998
Johansson U, Hansson-Georgiadis H, Hultman P
Abstract excerpt
BACKGROUND: Mercury causes in mouse strains of the H-2s haplotype an autoimmune syndrome with antibodies to the nucleolar protein fibrillarin and systemic immune complex (IC) deposits. Other strains, like BALB/C (H-2d), develop only IC deposits, and most strains are resistant. However, mercury activates the murine immune system and causes lymphoproliferation in most strains: H-2s strains are high-responders also...
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