Article
Genome-wide allelotype analysis of sporadic primary nasopharyngeal carcinoma from southern China.
International journal of oncology - 1 Dec 2000
Shao J Y, Wang H Y, Huang X M, Feng Q S, Huang P, Feng B J, Huang L X, Yu X J, Li J T, Hu L F, Ernberg I, Zeng Y X
Abstract excerpt
Nasopharyngeal carcinoma (NPC) is one of the most common malignant tumors in Southern China, especially in the Guangdong area. To demonstrate a comprehensive profile of loss of heterozygosity (LOH) in NPC, we applied a large panel of 382 microsatellite polymorphism markers covering all the 22 autosomes in 98 cases of sporadic primary NPC. Of the 335 informative markers, 83 loci showed high level of LOH (presence...
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