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Article

Identification of distinct regions of allelic loss on chromosome 13q in nasopharyngeal cancer from paraffin embedded tissues.

International journal of cancer - 8 Oct 1999

Mutirangura A, Charuruks N, Shuangshoti S, Sakdikul S, Chatsantikul R, Pornthanakasem W, Sriuranpong V, Supiyaphun P, Voravud N

Abstract excerpt

Our main purpose was to identify tumor suppressor gene loci on chromosome 13 responsible for nasopharyngeal cancer (NPC) development by analyzing loss of heterozygosity (LOH) and RB protein expression in paraffin embedded tissues. Normal and tumor DNA were extracted from microdissected samples, and their whole genomes were amplified using degenerate oligonucleotide primers. The polymerase chain reaction (PCR)...

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Source

Identifiers

PMID: 10471529
DOI: 10.1002/(sici)1097-0215(19991008)83:2<210::aid-ijc11>3.0.co;2-y

Genes

BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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