Article
[Precise map of allelic loss on chromosome 3p14 in nasopharyngeal carcinoma].
Zhonghua er bi yan hou ke za zhi - 1 Oct 2000
Deng Y, Tian F, Yang X, Xie D, Lu Y, Shao X, Chen Z
Abstract excerpt
OBJECTIVE: To determine the precise allelic loss on chromosome 3p14 and discuss the possible relations between loss of heterozygosity (LOH) and EBV infection, clinical stage and clinic-pathology of nasopharyngeal carcinoma (NPC). METHODS: Six high dense microsatellite marker on chromosome 3p14 were selected to examine LOH in 32 cases of NPC. RESULTS: 23 of 32 (71.9%) tumors were deleted for at least one locus of...
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