Article
Frequent loss of heterozygosity at 3p25-p26 is associated with invasive oral squamous cell carcinoma.
Journal of human genetics - 1 Jan 2001
Kayahara H, Yamagata H, Tanioka H, Miki T, Hamakawa H
Abstract excerpt
Recent molecular evidence suggests that allelic deletions of chromosomes are involved in the carcinogenesis of various neoplasms, including oral squamous cell carcinoma (OSCC). To determine the role of 3p deletions in Japanese OSCC and to define the localization of putative tumor suppressor genes, we initially examined loss of heterozygosity (LOH), using nine microsatellite markers in 36 OSCCs and 28 oral...
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