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Article

Contralateral breast cancer risk is influenced by the age at onset in BRCA1-associated breast cancer.

British journal of cancer - 1 Aug 2000

Verhoog L C, Brekelmans C T, Seynaeve C, Meijers-Heijboer E J, Klijn J G

Abstract excerpt

BRCA1/2 mutation carriers diagnosed with breast cancer have a strongly elevated life-time risk of developing a contralateral tumour. We studied the contralateral breast cancer risk in 164 patients from 83 families with a proven BRCA1 mutation in relation to the age at diagnosis of the first primary breast cancer. In the actuarial outcomes after 10 years' follow-up, 40% of the 124 BRCA1-patients diagnosed with...

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Identifiers

PMID: 10917555
DOI: 10.1054/bjoc.2000.1239
PMCID: PMC2374577

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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