Risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: a 30-year semi-prospective analysis.

doi:10.1007/s10689-015-9825-9

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Article

Risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: a 30-year semi-prospective analysis.

Familial cancer - 1 Dec 2015

Basu N N, Ingham S, Hodson J, Lalloo F, Bulman M, Howell A, Evans D G

Abstract excerpt

BRCA1 and BRCA2 mutation carriers have an increased risk of contralateral breast cancer after primary breast cancer. Risk reduction strategies are discussed after assessment of risk factors for developing contralateral breast cancer. We assessed potential risk factors that could be of use in clinical practice, including the novel use of single nucleotide polymorphisms (SNP) testing. 506 BRCA1 and 505 BRCA2...

Topics

Adult
BRCA1 Protein
BRCA2 Protein
Breast Neoplasms
Cross-Sectional Studies
Female
Follow-Up Studies
Genetic Predisposition to Disease
Heterozygote
Humans
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Staging

Polymorphism, Single Nucleotide

Prognosis

Prospective Studies

Retrospective Studies

Risk Factors

Time Factors

Source

Open in PubMed

Identifiers

PMID: 26239694
DOI: 10.1007/s10689-015-9825-9

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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