Article
Predictors of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers.
British journal of cancer - 26 Apr 2011
Metcalfe K, Gershman S, Lynch H T, Ghadirian P, Tung N, Kim-Sing C, Olopade O I, Domchek S, McLennan J, Eisen A, Foulkes W D, Rosen B, Sun P, Narod S A
Abstract excerpt
PURPOSE: The objective of this study was to estimate the risk of contralateral breast cancer in BRCA1 and BRCA2 carriers; and measure the extent to which host, family history, and cancer treatment-related factors modify the risk. PATIENTS AND METHODS: Patients were 810 women, with stage I or II breast cancer, for whom a BRCA1 or BRCA2 mutation had been identified in the family. Patients were followed from the...
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