Predictors of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers.

doi:10.1038/bjc.2011.120

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Article

Predictors of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers.

British journal of cancer - 26 Apr 2011

Metcalfe K, Gershman S, Lynch H T, Ghadirian P, Tung N, Kim-Sing C, Olopade O I, Domchek S, McLennan J, Eisen A, Foulkes W D, Rosen B, Sun P, Narod S A

Abstract excerpt

PURPOSE: The objective of this study was to estimate the risk of contralateral breast cancer in BRCA1 and BRCA2 carriers; and measure the extent to which host, family history, and cancer treatment-related factors modify the risk. PATIENTS AND METHODS: Patients were 810 women, with stage I or II breast cancer, for whom a BRCA1 or BRCA2 mutation had been identified in the family. Patients were followed from the...

Topics

Adult
Age Factors
Aged
Breast Neoplasms
Cohort Studies
Female
Genes, BRCA1
Genes, BRCA2
Genetic Predisposition to Disease
Heterozygote
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Mutation

Neoplasms, Second Primary

Odds Ratio

Ovariectomy

Predictive Value of Tests

Risk Assessment

Source

Open in PubMed Open full text

Identifiers

PMID: 21487411
DOI: 10.1038/bjc.2011.120
PMCID: PMC3101934

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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