Article
Reduced hippocampal volumes and memory loss in patients with early- and late-onset depression.
The British journal of psychiatry : the journal of mental science - 1 Mar 2005
Hickie Ian, Naismith Sharon, Ward Philip B, Turner Keelin, Scott Elizabeth, Mitchell Philip, Wilhelm Kay, Parker Gordon
Abstract excerpt
BACKGROUND: Hippocampal volume reduction has been reported inconsistently in people with major depression. AIMS: To evaluate the interrelationships between hippocampal volumes, memory and key clinical, vascular and genetic risk factors. METHOD: Totals of 66 people with depression and 20 control participants underwent magnetic resonance imaging and clinical assessment. Measures of depression severity, psychomotor...
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