Article
APOE genotype and hippocampal volume change in geriatric depression.
Biological psychiatry - 1 Mar 2002
Kim Do Hoon, Payne Martha E, Levy Robert M, MacFall James R, Steffens David C
Abstract excerpt
BACKGROUND: Apolipoprotein E has been associated with hippocampal volume loss in Alzheimer's disease and in elderly controls. In this study, we examined the role of apolipoprotein E and hippocampal volume change in 45 older nondemented depressed subjects. All had baseline and 2-year magnetic resonance imaging scans. METHODS: Hippocampal volumes were determined using a semiautomated method. RESULTS: Compared with...
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