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Article

Modeling of the TCR-MHC-peptide complex.

Journal of molecular biology - 28 Jul 2000

Michielin O, Luescher I, Karplus M

Abstract excerpt

The methodology for generating a homology model of the T1 TCR-PbCS-K(d) class I major histocompatibility complex (MHC) class I complex is presented. The resulting model provides a qualitative explanation of the effect of over 50 different mutations in the region of the complementarity determining region (CDR) loops of the T cell receptor (TCR), the peptide and the MHC's alpha(1)/alpha(2) helices. The peptide is...

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Source

Identifiers

PMID: 10903865
DOI: 10.1006/jmbi.2000.3788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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