An analysis of sequence variation in the beta chain framework and complementarity determining regions of an allo-reactive T cell receptor.

doi:10.1016/0161-5890(94)90179-1

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Article

An analysis of sequence variation in the beta chain framework and complementarity determining regions of an allo-reactive T cell receptor.

Molecular immunology - 1 Jun 1994

DiGiusto D L, Palmer E

Abstract excerpt

Current models of T cell receptor (TCR) structure are generally based on the homology observed between the TCR and the immunoglobulins. Furthermore, these models have predicted the locations of framework and complementarity determining regions within the alpha- and beta-chain variable regions. In...

Topics

Amino Acid Sequence
Animals
DNA Mutational Analysis
Epitopes
Genetic Variation
Hybridomas
Mice
Molecular Sequence Data
Mutagenesis, Site-Directed
Receptors, Antigen, T-Cell, alpha-beta
Transfection

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