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Article

TCRep 3D: an automated in silico approach to study the structural properties of TCR repertoires.

PloS one - 1 Jan 2011

Leimgruber Antoine, Ferber Mathias, Irving Melita, Hussain-Kahn Hamid, Wieckowski Sébastien, Derré Laurent, Rufer Nathalie, Zoete Vincent, Michielin Olivier

Abstract excerpt

TCRep 3D is an automated systematic approach for TCR-peptide-MHC class I structure prediction, based on homology and ab initio modeling. It has been considerably generalized from former studies to be applicable to large repertoires of TCR. First, the location of the complementary determining regions of the target sequences are automatically identified by a sequence alignment strategy against a database of TCR Vα...

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Identifiers

PMID: 22053188
DOI: 10.1371/journal.pone.0026301
PMCID: PMC3203878

Genes

CDR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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