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Article

Direct interaction of NF-E2 with hypersensitive site 2 of the β-globin locus control region in living cells

1 Jul 2000

Abstract excerpt

The human beta-globin locus control region (LCR) confers high-level, tissue-specific expression to the beta-globin genes. Tandem Maf recognition elements (MAREs) within the hypersensitive site 2 (HS2) subregion of the LCR are important for the strong enhancer activity of the LCR. Multiple proteins are capable of interacting with these sites in vitro, including the erythroid cell- and megakaryocyte-specific...

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PMID: 10891470
DOI: 10.1182/blood.v96.1.334

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Direct interaction of NF-E2 with hypersensitive site 2 of the β-globin locus control region in living cellsPMID 10891470Read ↗

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