Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein.

Nature - 22 Apr 1993

Andrews N C, Erdjument-Bromage H, Davidson M B, Tempst P, Orkin S H

Abstract excerpt

Expression of globin genes in developing erythroid cells is controlled by upstream locus control regions. Activity of these regions in vivo requires an erythroid-specific nuclear factor (NF-E2) that binds AP-1-like recognition sites. Its tissue-specific component (p45 NF-E2) has been characterized by complementary DNA cloning as a new basic region-leucine zipper protein which dimerizes with a ubiquitous partner...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cell Line

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cloning, Molecular

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 8469283
DOI: 10.1038/362722a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein.PMID 8469283Read ↗

Induction of Human Fetal Globin Gene Expression by a Novel Erythroid Factor, NF-E4Semantic proximity Read ↗

NF-Y Recruits Both Transcription Activator and Repressor to Modulate Tissue- and Developmental Stage-Specific Expression of Human γ-Globin GeneSemantic proximity Read ↗

The genetics of the E2F family of transcription factors: shared functions and unique roles.Semantic proximity Read ↗

Cloning and functional characterization of LCR-F1: a bZIP transcription factor that activates erythroid-specific, human globin gene expression.Semantic proximity Read ↗

Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NF-E2.Semantic proximity Read ↗

The GATA-E box-GATA motif in the EKLF promoter is required for in vivo expression.Semantic proximity Read ↗

Isolation and characterization of zebrafish NFE2.Semantic proximity Read ↗

Functional interaction of CP2 with GATA-1 in the regulation of erythroid promoters.Semantic proximity Read ↗

The long terminal repeat (LTR) of ERV-9 human endogenous retrovirus binds to NF-Y in the assembly of an active LTR enhancer complex NF-Y/MZF1/GATA-2.Semantic proximity Read ↗

AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2V617F-independent overexpression of NF-E2Semantic proximity Read ↗

Direct interaction of NF-E2 with hypersensitive site 2 of the β-globin locus control region in living cellsSemantic proximity Read ↗

GPS2 promotes erythroid differentiation by control of the stability of EKLF proteinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.