Article
Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein.
Nature - 22 Apr 1993
Andrews N C, Erdjument-Bromage H, Davidson M B, Tempst P, Orkin S H
Abstract excerpt
Expression of globin genes in developing erythroid cells is controlled by upstream locus control regions. Activity of these regions in vivo requires an erythroid-specific nuclear factor (NF-E2) that binds AP-1-like recognition sites. Its tissue-specific component (p45 NF-E2) has been characterize...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Cell Line
- Cloning, Molecular
- Consensus Sequence
- DNA
- DNA-Binding Proteins
- Erythrocytes
- Erythroid-Specific DNA-Binding Factors
- Globins
- Hematopoiesis
- Leucine Zippers
- Leukemia, Erythroblastic, Acute
- Mice
- Molecular Sequence Data
- Mutation