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Article

Replicability and recurrence in the experimental evolution of a group I ribozyme.

Molecular biology and evolution - 1 Jul 2000

Hanczyc M M, Dorit R L

Abstract excerpt

In order to explore the variety of possible responses available to a ribozyme population evolving a novel phenotype, five Tetrahymena thermophila group I intron ribozyme pools were evolved in parallel for cleavage of a DNA oligonucleotide. These ribozyme populations were propagated under identical conditions and characterized when they reached apparent phenotypic plateaus; the populations that reached the highest...

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PMID: 10889218
DOI: 10.1093/oxfordjournals.molbev.a026386

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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