Article
Analysis of the TCRBV repertoire of T cells in normal, human skin: evidence for a restricted diversity.
The Journal of investigative dermatology - 1 Jul 2000
Menssen A, Vollmer S, Trommler P, Sander C, Prinz J C
Abstract excerpt
Alpha beta T cells constitute an important component in the first line of immunologic defense in human skin. In order to determine the local selection forces driving T cell diversity, we studied the T cell receptor repertoire in normal human skin and compared it with that of matched blood samples. Using semiquantitative reverse transcription-polymerase chain reaction the expression of T cell receptor beta-chain V...
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