Article
High-throughput sequencing reveals the diversity of TCR β chain CDR3 repertoire in patients with severe acne.
Molecular immunology - 1 Apr 2020
Shao Lei, Liu Yumei, Mei Junpu, Li Dongmei, Chen Lijie, Pan Qingli, Zhang Shujuan, Dai Xiangnong, Liang Jingyao, Sun Silong, Wang Jianqin
Abstract excerpt
Acne is a common chronic inflammatory skin disease, and the inflammation immune response runs through all stages of acne lesions. In this study, we use a combination of multiplex-PCR and high-throughput sequencing technologies to analyze T cell receptor β chain CDR3 (complementarity-determining region 3) in peripheral blood isolated from severe acne patients. Once compared with healthy controls, we propose to...
Topics
Join the communities discussing this publication.