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Article

Polarity exchange at the interface of regulators of G protein signaling with G protein alpha-subunits.

The Journal of biological chemistry - 15 Sept 2000

Wieland T, Bahtijari N, Zhou X B, Kleuss C, Simon M I

Abstract excerpt

RGS proteins are GTPase-activating proteins (GAPs) for G protein alpha-subunits. This GAP activity is mediated by the interaction of conserved residues on regulator of G protein signaling (RGS) proteins and Galpha-subunits. We mutated the important contact sites Glu-89, Asn-90, and Asn-130 in RGS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10878019
DOI: 10.1074/jbc.M004187200

Genes

RGS16
RGS4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10878019-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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