Article
The mutation in the N-terminal domain of RGS4 disrupts PA-conferred inhibitory effect on GAP activity.
Bioscience reports - 1 Aug 2003
Ou-Yang Ying-Shi, Tu Yaping, Yang Fuyu
Abstract excerpt
Regulator of G protein signaling (RGS) proteins are GTPase-activating proteins (GAP) for G protein alpha-subunits and are thought to be responsible for rapid deactivation of G protein mediated signaling pathway. In this present study, we demonstrate that PA is the most efficient candidate to inhi...
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