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Article

Differential effects of RGS proteins on G alpha(q) and G alpha(11) activity.

Cellular signalling - 1 Jan 2007

Ladds Graham, Goddard Alan, Hill Claire, Thornton Steven, Davey John

Abstract excerpt

Heterotrimeric G proteins play a pivotal role in GPCR signalling; they link receptors to intracellular effectors and their inactivation by RGS proteins is a key factor in resetting the pathway following stimulation. The precise GPCR:G protein:RGS combination determines the nature and duration of the response. Investigating the activity of particular combinations is difficult in cells which contain multiples of...

Read the complete abstract on PubMed

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Source

Identifiers

PMID: 16843638
DOI: 10.1016/j.cellsig.2006.05.027

Genes

RGS2
RGS3
RGS16
RGS5
RGS1
RGS4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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