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Article

Alzheimer's disease: analyzing the missing heritability.

PloS one - 1 Jan 2013

Ridge Perry G, Mukherjee Shubhabrata, Crane Paul K, Kauwe John S K

Abstract excerpt

Alzheimer's disease (AD) is a complex disorder influenced by environmental and genetic factors. Recent work has identified 11 AD markers in 10 loci. We used Genome-wide Complex Trait Analysis to analyze >2 million SNPs for 10,922 individuals from the Alzheimer's Disease Genetics Consortium to assess the phenotypic variance explained first by known late-onset AD loci, and then by all SNPs in the Alzheimer's...

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Identifiers

PMID: 24244562
DOI: 10.1371/journal.pone.0079771
PMCID: PMC3820606

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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