Article
A model for susceptibility polymorphisms for complex diseases: apolipoprotein E and Alzheimer disease.
Neurogenetics - 1 May 1997
Roses A D
Abstract excerpt
Apolipoprotein E (APOE) polymorphisms are associated with variable risk and age of onset distributions for the common form of Alzheimer disease. Clinical genetic applications of APOE genotyping differ from those of family-specific mutations because the APOE genotypes are universally distributed in all populations, with ethnic and racial variations in relative allele frequencies. The association of a common...
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