Article
SNP association studies in Alzheimer's disease highlight problems for complex disease analysis.
Trends in genetics : TIG - 1 Jul 2001
Emahazion T, Feuk L, Jobs M, Sawyer S L, Fredman D, St Clair D, Prince J A, Brookes A J
Abstract excerpt
Genetic linkage and association analyses are two distinct approaches to understanding the genetic etiology of complex disease. Association analysis has become particularly popular in recent times, but the true utility of the strategy remains uncertain. To try to gain better insight into the relevant issues, we have used genetic association analysis to explore the etiology of Alzheimer's disease. Our empirical...
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