Article
Evolution of introns and exons of class II major histocompatibility complex genes of vertebrates.
Immunogenetics - 1 May 2000
Hughes A L
Abstract excerpt
The phylogenetic relationships and patterns of nucleotide substitution were compared for introns and exons of class II major histocompatibility complex (MHC) genes in three datasets: human DRB1, human DQA1, and cyprinid fish DAB1. In both human DRB1 and cyprinid DAB1, there was strong evidence that recombination events between alleles have occurred in such a way that intron and exon sequences of a given allele do...
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