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Article

Evolutionary relationships between HLA-B alleles as indicated by an analysis of intron sequences.

Tissue antigens - 1 Feb 1999

Gomez-Casado E, Vargas-Alarcón G, Martinez-Laso J, Granados J, Varela P, Alegre R, Longás J, González-Hevilla M, Martín-Villa J M, Arnaiz-Villena A

Abstract excerpt

The HLA-B locus is the most polymorphic of the class I genes encoded within the human major histocompatibility complex. This polymorphism is mainly located in exons 2 and 3, which code for the molecule's alpha1 and alpha2 domains and includes the antigenic peptide binding site. However, information about adjacent non-coding regions (introns 1 and 2) has not been extensively reported but could be very important in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 10090615
DOI: 10.1034/j.1399-0039.1999.530205.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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