Common chimpanzees have greater diversity than humans at two of the three highly polymorphic MHC class I genes.

doi:10.1007/s002510050639

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Common chimpanzees have greater diversity than humans at two of the three highly polymorphic MHC class I genes.

Immunogenetics - 1 May 2000

Adams E J, Cooper S, Thomson G, Parham P

Abstract excerpt

MHC class I polymorphism improves the defense of vertebrate species against viruses and other intracellular pathogens. To see how polymorphism at the same class I genes can evolve in different species we compared the MHC-A, MHC-B, and MHC-C loci of common chimpanzees and humans. Diversity in 23 Patr-A, 32 Patr-B, and 18 Patr-C alleles obtained from study of 48 chimpanzees was compared to diversity in 66 HLA-A,...

Topics

Alleles
Animals
Base Sequence
Cell Line
Codon
Genes, MHC Class I
Genetic Markers
Humans
Molecular Sequence Data
Multigene Family
Pan troglodytes
Polymorphism, Genetic
Sequence Homology, Nucleic Acid
Species Specificity

Source

Open in PubMed

Identifiers

PMID: 10866107
DOI: 10.1007/s002510050639

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics