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Article

Common chimpanzees have greater diversity than humans at two of the three highly polymorphic MHC class I genes.

Immunogenetics - 1 May 2000

Adams E J, Cooper S, Thomson G, Parham P

Abstract excerpt

MHC class I polymorphism improves the defense of vertebrate species against viruses and other intracellular pathogens. To see how polymorphism at the same class I genes can evolve in different species we compared the MHC-A, MHC-B, and MHC-C loci of common chimpanzees and humans. Diversity in 23 Patr-A, 32 Patr-B, and 18 Patr-C alleles obtained from study of 48 chimpanzees was compared to diversity in 66 HLA-A,...

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PMID: 10866107
DOI: 10.1007/s002510050639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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