Genomic analysis of common chimpanzee major histocompatibility complex class I genes.

doi:10.1007/s002510100318

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Article

Genomic analysis of common chimpanzee major histocompatibility complex class I genes.

Immunogenetics - 1 Apr 2001

Adams E J, Parham P

Abstract excerpt

To investigate how MHC class I genes have changed in the approximately 5 million years since chimpanzees and humans diverged, we characterized six genomic fragments ranging in size from 5.1 to 6.1 kb, each containing the complete coding region, introns, and flanking regions of one of the following chimpanzee class I genes: Patr-A, Patr-E, Patr-F, Patr-G, Patr-H, and Patr-J. In humans, these genes are closely...

Topics

Animals
Base Sequence
Cell Line, Transformed
Chromosome Mapping
DNA, Complementary
Genes, MHC Class I
Genetic Variation
Molecular Sequence Data
Pan troglodytes
Species Specificity

Source

Open in PubMed

Identifiers

PMID: 11398964
DOI: 10.1007/s002510100318

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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