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Article

Differences in MHC-B diversity and KIR epitopes in two populations of wild chimpanzees.

Immunogenetics - 1 Nov 2019

Maibach Vincent, Langergraber Kevin, Leendertz Fabian H, Wittig Roman M, Vigilant Linda

Abstract excerpt

The major histocompatibility complex (MHC) class I genes play a critical role within the immune system, both by the presentation of antigens from intracellular pathogens to immunocompetent cells and by the interaction with killer cell immunoglobulin-like receptors (KIR) on natural killer cells (NK cells). Genes of the MHC are highly diverse, and MHC variation can have effects on the immune functionality of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31797008
DOI: 10.1007/s00251-019-01148-3
PMCID: PMC6900261

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