MHC class I diversity in chimpanzees and bonobos.

doi:10.1007/s00251-017-0990-x

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Article

MHC class I diversity in chimpanzees and bonobos.

Immunogenetics - 1 Oct 2017

Maibach Vincent, Hans Jörg B, Hvilsom Christina, Marques-Bonet Tomas, Vigilant Linda

Abstract excerpt

Major histocompatibility complex (MHC) class I genes are critically involved in the defense against intracellular pathogens. MHC diversity comparisons among samples of closely related taxa may reveal traces of past or ongoing selective processes. The bonobo and chimpanzee are the closest living evolutionary relatives of humans and last shared a common ancestor some 1 mya. However, little is known concerning MHC...

Topics

Alleles
Animals
Biological Evolution
Female
Gene Frequency
Genetic Variation
Genotype
Genotyping Techniques
High-Throughput Nucleotide Sequencing
Histocompatibility Antigens Class I
Humans
Male
Open Reading Frames
Pan paniscus
Pan troglodytes
Phylogeny

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Identifiers

PMID: 28623392
DOI: 10.1007/s00251-017-0990-x
PMCID: PMC5597694

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