Article
Major histocompatibility complex class I diversity in a West African chimpanzee population: implications for HIV research.
Immunogenetics - 1 May 2000
de Groot N G, Otting N, Argüello R, Watkins D I, Doxiadis G G, Madrigal J A, Bontrop R E
Abstract excerpt
Human immunodeficiency virus (HIV) poses a major threat to humankind. And though, like humans, chimpanzees are susceptible to HIV infection, they are considered to be resistant to the development of the acquired immune deficiency syndrome (AIDS). Little is known about major histocompatibility complex (MHC) class I diversity in chimpanzee populations and, moreover, whether qualitative aspects of Patr class I...
Topics
- Acquired Immunodeficiency Syndrome
- Africa, Western
- Amino Acid Sequence
- Animals
- Evolution, Molecular
- Gene Frequency
- Genes, MHC Class I
- Genetic Markers
- Genetic Predisposition to Disease
- HIV
- Heterozygote
- Histocompatibility Antigens Class I
- Histocompatibility Testing