Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Conservation of sigma-core RNA polymerase proximity relationships between the enhancer-independent and enhancer-dependent sigma classes.

The EMBO journal - 15 Jun 2000

Wigneshweraraj S R, Fujita N, Ishihama A, Buck M

Abstract excerpt

Two distinct classes of RNA polymerase sigma factors (sigma) exist in bacteria and are largely unrelated in primary amino acid sequence and their modes of transcription activation. Using tethered iron chelate (Fe-BABE) derivatives of the enhancer-dependent sigma(54), we mapped several sites of proximity to the beta and beta' subunits of the core RNA polymerase. Remarkably, most sites localized to those previously...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Directed RNA Polymerases
Share to DNA Footprinting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Edetic Acid

Share to Enhancer Elements, Genetic

Share to Holoenzymes

Share to Organometallic Compounds

Share to RNA Polymerase Sigma 54

Share to Sigma Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 10856247
DOI: 10.1093/emboj/19.12.3038
PMCID: PMC203346

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Conservation of sigma-core RNA polymerase proximity relationships between the enhancer-independent and enhancer-dependent sigma classes.PMID 10856247Read ↗

Regulatory sequences in sigma 54 localise near the start of DNA melting.Semantic proximity Read ↗

Converting Escherichia coli RNA polymerase into an enhancer-responsive enzyme: role of an NH2-terminal leucine patch in sigma 54.Semantic proximity Read ↗

Sequences within the DNA cross-linking patch of sigma 54 involved in promoter recognition, sigma isomerization, and open complex formation.Semantic proximity Read ↗

Mutant forms of Salmonella typhimurium sigma54 defective in transcription initiation but not promoter binding activity.Semantic proximity Read ↗

Open complex scrunching before nucleotide addition accounts for the unusual transcription start site of E. coli ribosomal RNA promoters.Semantic proximity Read ↗

Multiple roles of the RNA polymerase beta subunit flap domain in sigma 54-dependent transcription.Semantic proximity Read ↗

In vitro roles of invariant helix-turn-helix motif residue R383 in sigma(54) (sigma(N)).Semantic proximity Read ↗

Compilation and analysis of sigma(54)-dependent promoter sequences.Semantic proximity Read ↗

An aromatic residue switch in enhancer-dependent bacterial RNA polymerase controls transcription intermediate complex activity.Semantic proximity Read ↗

Promoter activation by repositioning of RNA polymerase.Semantic proximity Read ↗

Mutations in the CRE pocket of bacterial RNA polymerase affect multiple steps of transcription.Semantic proximity Read ↗

Mapping ATP-dependent activation at a sigma54 promoter.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.