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Article

Mapping ATP-dependent activation at a sigma54 promoter.

The Journal of biological chemistry - 3 Nov 2006

Leach Robert N, Gell Christopher, Wigneshweraraj Sivaramesh, Buck Martin, Smith Alastair, Stockley Peter George

Abstract excerpt

The sigma(54) promoter specificity factor is distinct from other bacterial RNA polymerase (RNAP) sigma factors in that it forms a transcriptionally silent closed complex upon promoter binding. Transcriptional activation occurs through a nucleotide-dependent isomerization of sigma(54), mediated via its interactions with an enhancer-binding activator protein that utilizes the energy released in ATP hydrolysis to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Bacterial

Share to Fluorescence Resonance Energy Transfer

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Share to Promoter Regions, Genetic

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Share to RNA Polymerase Sigma 54

Source

Identifiers

PMID: 16926155
DOI: 10.1074/jbc.M605731200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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