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Article

Multiple roles of the RNA polymerase beta subunit flap domain in sigma 54-dependent transcription.

The Journal of biological chemistry - 31 Jan 2003

Wigneshweraraj Siva R, Kuznedelov Konstantin, Severinov Konstantin, Buck Martin

Abstract excerpt

Recent determinations of the structures of the bacterial RNA polymerase (RNAP) and promoter complex thereof establish that RNAP functions as a complex molecular machine that contains distinct structural modules that undergo major conformational changes during transcription. However, the contribution of the RNAP structural modules to transcription remains poorly understood. The bacterial core RNAP (alpha(2)beta...

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PMID: 12424241
DOI: 10.1074/jbc.M209442200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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