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Article

Genetic analysis of multiple sporadic colon carcinomas from a single patient.

International journal of colorectal disease - 1 Apr 2000

Barnetson R A, Symons P, Robinson B G, Schnitzler M

Abstract excerpt

At least two separate genetic pathways of carcinogenesis in sporadic colon cancer involving the accumulation of mutations at various genetic loci have been described. About 15% of sporadic colorectal carcinomas arise via a mechanism associated with microsatellite instability (MSI) and mutations in transforming growth factor beta receptor II (TGFbetaRII), insulin-like growth factor II receptor (IGFIIR) and BAX,...

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Source

Identifiers

PMID: 10855548
DOI: 10.1007/s003840050237

Genes

BAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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