Article
Two types of sporadic multiple colorectal cancers with and without HNPCC-like genetic instability.
Hepato-gastroenterology - 1 Jan 2000
Komura K, Masuda H, Esumi M
Abstract excerpt
BACKGROUND/AIMS: Sporadic multiple colorectal cancers (MCCs) potentially have similar genetic alterations to hereditary nonpolyposis colorectal cancers (HNPCCs), but genetically unstable MCCs other than HNPCCs are not well characterized. We report the frequency of HNPCC-like sporadic multiple colon cancers and their characterization as for HNPCC-related gene mutations. METHODOLOGY: Microsatellite instability...
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