Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic analysis of multiple synchronous lesions of the colon adenoma–carcinoma sequence

1 Apr 2000

Abstract excerpt

The colorectal adenoma-carcinoma sequence represents a well-known paradigm for the sequential development of cancer driven by the accumulation of genomic defects. Although the colorectal adenoma-carcinoma sequence is well investigated, studies about tumours of different dignity co-existent in the same patient are seldom. In order to address the distribution of genetic alterations in different lesions of the same...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Genetic factors in colorectal cancer

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 10755401
DOI: 10.1054/bjoc.1999.1091

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic analysis of multiple synchronous lesions of the colon adenoma–carcinoma sequencePMID 10755401Read ↗

The colorectal adenoma-carcinoma sequence.Semantic proximity Read ↗

Similarities of molecular genetic changes in synchronous and metachronous colorectal cancers are limited and related to the cancers' proximities to each other.Semantic proximity Read ↗

Cancer of the microsatellite mutator phenotype.Semantic proximity Read ↗

Genetic analysis of multiple sporadic colon carcinomas from a single patient.Semantic proximity Read ↗

Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas.Semantic proximity Read ↗

DNA demethylation in normal colon tissue predicts predisposition to multiple cancers.Semantic proximity Read ↗

Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer.Semantic proximity Read ↗

Endometrial and colorectal tumors from patients with hereditary nonpolyposis colon cancer display different patterns of microsatellite instability.Semantic proximity Read ↗

Colorectal adenoma and cancer divergence. Evidence of multilineage progression.Semantic proximity Read ↗

Frequent loss of hMLH1 by promoter hypermethylation leads to microsatellite instability in adenomatous polyps of patients with a single first-degree member affected by colon cancer.Semantic proximity Read ↗

The sequential accumulation of genetic alterations characteristic of the colorectal adenoma-carcinoma sequence does not occur between gastric adenoma and adenocarcinoma.Semantic proximity Read ↗

Multiple detection of genetic alterations in tumors and stool.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.