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Article

Testing cyclin specificity in the exit from mitosis.

Molecular and cellular biology - 1 Jul 2000

Jacobson M D, Gray S, Yuste-Rojas M, Cross F R

Abstract excerpt

Cyclical inactivation of B-type cyclins has been proposed to be required for alternating DNA replication and mitosis. Destruction box-dependent Clb5p degradation is strongly increased in mitotic cells, and constitutive overexpression of Clb5p lacking the destruction box resulted in rapid accumulation of inviable cells, frequently multiply budded, with DNA contents ranging from unreplicated to apparently fully...

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Identifiers

PMID: 10848575
DOI: 10.1128/MCB.20.13.4483-4493.2000
PMCID: PMC85822

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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