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Article

The yeast mitotic cyclin Clb2 cannot substitute for S phase cyclins in replication origin firing.

EMBO reports - 1 Dec 2000

Donaldson A D

Abstract excerpt

Cyclin-dependent kinases (CDKs) drive the cell cycle, central to which is the accurate control of chromosome replication. In Saccharomyces cerevisiae, six closely related B-type cyclins (Clb1-6) drive the events of S phase and mitosis. Either Clb5 or Clb6 can activate early-firing replication origins, whereas only Clb5 can activate late origins. Clb1-4 are expressed later in the cell cycle. Whether Clb cyclins...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11263495
DOI: 10.1093/embo-reports/kvd108
PMCID: PMC1083780

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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