Article
A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis.
Cell - 5 Apr 1991
Ghiara J B, Richardson H E, Sugimoto K, Henze M, Lew D J, Wittenberg C, Reed S I
Abstract excerpt
A cyclin B homolog was identified in Saccharomyces cerevisiae using degenerate oligonucleotides and the polymerase chain reaction. The protein, designated Scb1, has a high degree of similarity with B-type cyclins from organisms ranging from fission yeast to human. Levels of SCB1 mRNA and protein...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Blotting, Northern
- Cell Cycle
- Cyclin B
- Cyclins
- DNA, Fungal
- Enzyme Activation
- Fungal Proteins
- Genes, Fungal
- Mitosis
- Molecular Sequence Data
- Phenotype
- Polymerase Chain Reaction
- Protamine Kinase
- Protein Kinases
- RNA, Fungal