Article
Compartmentalization of the functions and regulation of the mitotic cyclin Clb2 in S. cerevisiae.
Journal of cell science - 15 Feb 2007
Eluère Raïssa, Offner Nicolas, Varlet Isabelle, Motteux Olivia, Signon Laurence, Picard André, Bailly Eric, Simon Marie-Noëlle
Abstract excerpt
Orderly progression through the eukaryotic cell cycle is a complex process involving both regulation of cyclin dependent kinase activity and control of specific substrate-Cdk interactions. In Saccharomyces cerevisiae, the mitotic cyclin Clb2 has a central role in regulating the onset of anaphase and in maintaining the cellular shape of the bud by inhibiting growth polarization induced in G1. However, how Clb2 and...
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