Diversity of Human αβ T Cell Receptors

Abstract excerpt

(a = alpha) \nArstila et al. (1) estimated an average diversity \nof 9 * 10^5 different b chains and 4.5 * \n10^5 different a chains in the human nai¨ve T \ncell repertoire. To calculate the total T cell \nrepertoire diversity, the b-chain diversity was \nestimated within a certain variable (V) gene \nfamily, Va12^+, comprising 2.5% of the total \na-chain repertoire. Finding in this particular \nfamily an...

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