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Article

A direct estimate of the human alphabeta T cell receptor diversity.

Science (New York, N.Y.) - 29 Oct 1999

Arstila T P, Casrouge A, Baron V, Even J, Kanellopoulos J, Kourilsky P

Abstract excerpt

Generation and maintenance of an effective repertoire of T cell antigen receptors are essential to the immune system, yet the number of distinct T cell receptors (TCRs) expressed by the estimated 10(12) T cells in the human body is not known. In this study, TCR gene amplification and sequencing showed that there are about 10(6) different beta chains in the blood, each pairing, on the average, with at least 25...

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Share to Gene Rearrangement, T-Lymphocyte
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immune Cell Function and Interaction

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Share to Receptors, Antigen, T-Cell, alpha-beta

Share to T-cell and B-cell Immunology

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Source

Identifiers

PMID: 10542151
DOI: 10.1126/science.286.5441.958

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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