Article
Receptor selection in B and T lymphocytes.
Annual review of immunology - 1 Jan 2000
Nemazee D
Abstract excerpt
The process of clonal selection is a central feature of the immune system, but immune specificity is also regulated by receptor selection, in which the fate of a lymphocyte's antigen receptor is uncoupled from that of the cell itself. Whereas clonal selection controls cell death or survival in response to antigen receptor signaling, receptor selection regulates the process of V(D)J recombination, which can alter...
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