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Article

Regulation of autoreactive antibodies

6 Aug 2007

Abstract excerpt

PURPOSE OF REVIEW: Significant progress has been made over recent years in uncovering the B-cell tolerance mechanisms that control development of autoreactive antibodies. This review examines current knowledge on the regulation and selection of autoreactive B cells in mouse models, and in healthy humans and patients with autoimmune disorders. RECENT FINDINGS: Autoreactive B cells undergo stringent selection...

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PMID: 17762605
DOI: 10.1097/bor.0b013e328277ef3b

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