Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Shape of the Lymphocyte Receptor Repertoire: Lessons from the B Cell Receptor

1 Jan 2013

Abstract excerpt

Both the B cell receptor (BCR) and the T cell receptor (TCR) repertoires are generated through essentially identical processes of V(D)J recombination, exonuclease trimming of germline genes, and the random addition of non-template encoded nucleotides. The naïve TCR repertoire is constrained by thymic selection, and TCR repertoire studies have therefore focused strongly on the diversity of MHC-binding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Cell Function and Interaction
Share to Lymphoma Diagnosis and Treatment
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24032032
DOI: 10.3389/fimmu.2013.00263

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Shape of the Lymphocyte Receptor Repertoire: Lessons from the B Cell ReceptorPMID 24032032Read ↗

Receptor selection in B and T lymphocytes.Semantic proximity Read ↗

B cell receptor editing in tolerance and autoimmunitySemantic proximity Read ↗

B cell receptor repertoire abnormalities in autoimmune diseaseSemantic proximity Read ↗

A Public Database of Memory and Naive B-Cell Receptor SequencesSemantic proximity Read ↗

Practical guidelines for B-cell receptor repertoire sequencing analysisSemantic proximity Read ↗

Variable lymphocyte receptor F is generated via somatic diversification and expressed by lamprey T-like cellsSemantic proximity Read ↗

The Evolution and Structure of Atypical T Cell Receptors.Semantic proximity Read ↗

Combined Influence of B-Cell Receptor Rearrangement and Somatic Hypermutation on B-Cell Class-Switch Fate in Health and in Chronic Lymphocytic LeukemiaSemantic proximity Read ↗

The evolutionary and structural 'logic' of antigen receptor diversity.Semantic proximity Read ↗

Evolution of variable lymphocyte receptor B antibody loci in jawless vertebrates.Semantic proximity Read ↗

High-throughput sequencing of the T-cell receptor repertoire: pitfalls and opportunities.Semantic proximity Read ↗

Single Cell T Cell Receptor Sequencing: Techniques and Future ChallengesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.