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Article

Genetic variants in IL33 and IL1RL1 genes confer susceptibility to HBV-related liver cirrhosis in Chinese Han population.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2021

Ma Ning, Xu Mengyuan, Dong Yi, Yu Fengxue, Zhang Xiaolin, Gao Xia, Meng Yanxin, Gao Ping, Zhou Jin, Yuan Meina, Mi Yingjun, Qi Sufen, Li Lu, Liu Dianwu, Liu Wenxuan, Yang Lei

Abstract excerpt

INTRODUCTION: Previous studies indicate that the IL-33/ST2 pathway is involved in hepatitis B virus (HBV) -related liver diseases. This study aimed to determine the relationship between genetic variants in IL-33/ST2 pathway with susceptibility to liver cirrhosis. MATERIALS AND METHODS: A total of 2632 Han Chinese samples met the inclusion and exclusion criteria, including 840 negative controls (NeC), 691 chronic...

Topics

Adult
Aged
China
Female
Genetic Predisposition to Disease
Hepatitis B
Hepatitis B virus
Hepatitis B, Chronic
Humans
Interleukin-1 Receptor-Like 1 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interleukin-33

Liver Cirrhosis

Male

Middle Aged

Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 34197916
DOI: 10.1016/j.meegid.2021.104983

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-34197916-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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