Article
Interleukin-1 gene cluster polymorphisms and alcoholism in Spanish men.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000
Pastor Isabel J, Laso Francisco Javier, Romero Alfonso, González-Sarmiento Rogelio
Abstract excerpt
AIMS: In an attempt to explain differences in susceptibility to alcoholism and alcohol liver disease (ALD), different genes have been analysed, among them those encoding inflammatory cytokines. Thus, it has been reported recently that both the interleukin 1 receptor antagonist (IL1RN) and the IL1beta (IL1B) genes may influence the risk of ALD in Japanese alcoholics. We analysed the distribution of single...
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